This paper mainly focused on the potential use of polyurethane(PU) in ecological sand-fixation. A detailed investigation was conducted for illuminating both the sand-fixing properties and ecological effect of polyurethane, and for knowing PU better, the comparison between PU and polyvinyl acetate emulsion (PVAc) was also made in the related properties. The experimental results show that when the using concentration of PU and PVAc is above 2%, both the PU and PVAc present not only the sand stabilization strength to meet the requirement of sand-fixation, but also good thermal and freeze-thaw stability to withstand the big changes in temperature of Sandy Land. Moreover, PU and PVAc can both improve the water-holding capacity of sandy soil to benefit the growth of microorganisms and the improvement of seed germination rate. By comparison between PU and PVAc, it is found that PVAc is more helpful than PU for the growth of sandy soil microorganisms and the improvement of seed germination rate. However, the consolidated layer of PU with sand has more flexibility for further improving the resistance to wind erosion. And, PU has better water-holding capacity to promote the growth of sandy soil bacteria and prolong the survival of plants, but it delays seed germination to a certain extent.