Based on the field-synergistic principle of polymer plasticization, conveying, and mixing, a novel co-rotating twin-screw field-synergistic twisting element was designed and developed. This study aims to address technical bottlenecks such as low heat transfer efficiency, non-uniform temperature distribution, and local degradation of heat-sensitive materials during the co-rotating twin-screw extrusion process, thereby improving plasticization quality and mixing uniformity through structural optimization. Numerical simulations were conducted by using the computational fluid dynamics (CFD) software ANSYS Polyflow to compare the heat transfer performance, mixing performance, and synergistic effects among the twisting element, conventional screw element, and kneading block element. The results indicate that the twisting element exhibits superior heat transfer and mixing performance compared to the other two types of elements, attributed to the improved synergy between its velocity field and temperature field. By introducing a 90° twisted surface, the twisting element alters the direction of the velocity field, generating make the material flow radially along a twisted surface. This enhances the synergistic interaction between the velocity field and the temperature gradient field as well as the velocity gradient field, thereby intensifying heat and mass transfer. The unique structure of the twisting element facilitates effective local heat and particle mixing, improving the plasticization quality of the material.