In order to enhance the modification effect of silane coupling agent on silica, this paper proposed the design and application study of a novel silane coupling agent containing dithiocyclopentane. Firstly, a new silane coupling agent 5-(1, 2-dithiolan-3-yl)-N-(3-(triethoxysilylpropyl)propyl)valeramide (abbreviated as LATES) was synthesized by reacting lipoic acid and aminopropyltriethoxysilane through amidation reaction; then the surface of silica A200 was modified by hydrolysis condensation reaction. Finally, LATES- A200/NR rubber composites were prepared and characterized using different amounts of LATES-A200 as fillers. The results show that LATES can effectively enhance the dispersion of silica A200 in rubber, and the 10% LATES-A200₄₅/NR rubber composite with 45 parts per million of additive shows the best overall performance. Compared with the unmodified A200/NR, the tensile strength of 10% LATES-A200₄₅/NR rubber increases from 19.51 MPa to 25.74 MPa, and the tan δ at 60 ℃ decreases from 0.111 to 0.071, indicating a decrease in the rolling resistance of the rubber and an increase in the content of the binding rubber and crosslinking density. Under the same treatment method and addition amount, the effect of LATES-modified silica on performance of NR is better than that of Si69- modified silica, which can provide a new choice of additives for the development of rubber composites for green tires.